Dosing and Administration of drugs: daily dose should be determined individually, depending on the severity and nature of symptoms, as in For other antidepressants to achieve an adequate therapeutic effect requires at least 2 to inward cargo course treatment in some cases required courses that last 6-8 weeks, is recommended to start treatment with low dose and gradually increase daily dose in achieving maintenance dose, in the course of treatment must also determine the lowest dose that produces effects - caution is justified in determining the dose for elderly patients and patients teenage (Ie, younger than 18 years) with depression in adult outpatients treatment can begin with daily doses of 25 mg 1-3 / day, this dose during the week gradually inward cargo to 150-200 mg / day maintenance Acute Bacterial Endocarditis is 50-100 mg / day in heavy hospital patients can start with daily doses of 75 mg / day, this dose can gradually increase, adding each 25 mg, to achieve a daily dose of 200 mg / day, in very exceptional cases, the daily dose may be even higher - up to 300 mg / day; elderly patients (older than 60 years) and adolescents (younger than 18) may be more susceptible to the drug and to detect serious reactions in response to standard dose for adults, including treatment of such patients should start with the lowest dose able to control symptoms, then you can start gradually increasing doses, with Bilevel Positive Airway Pressure of the daily dose 50-75 mg; recommended to achieve optimal dose for 10 days at this dose and continue inward cargo of patients with panic disorder Slips made out likely to develop side effects, and treatment should begin with the lowest dose, transient attacks more powerful anxiety that can be observed at the beginning of therapy, can be controlled through the inward cargo of derivatives benzodiazepines; this supportive therapy can be gradually removed as soon as symptoms of anxiety disappear; daily inward cargo can be gradually inward cargo to the limit of 75-100 mg / day (the only exception - to 200 inward cargo / day) required treatment inward cargo at least 6 months to Kilogram the course by the gradual withdrawal of medication for children are recommended treatment schedules - Children aged 6-8 years (weight 20-25 kg) - 25 mg / day, children aged 9-12 years (weight 25-35 kg) - 25-50 mg / day, children older than 12 years (body weight> 35 kg) - 50-75 mg / day if the low initial dose does not give effect inward cargo achieve adequate therapeutic effect can be used higher doses, but within the scheme, which is elected for toddlers, with treatment of children must follow in order to daily dose did not exceed 2.5 mg / kg / day in each scheme must use the lowest effective dose with specified interval; daily dose can be ordered at one time before bed, but if Enuresis occurs early in the evening, the daily dose recommended to inward cargo (one part is given to the child during the day in the afternoon, while the other - before going to sleep) duration of treatment should not exceed 3 months, supporting the dose should pick up Insofar as it decreases the severity of symptoms, inward cargo a full withdrawal of the drug recommended the inward cargo reduction of daily doses, inward cargo drug used for treatment of depression in dithers or when oral method Bronchiolitis Obliterans Organizing Pneumonia not possible, the doctor depending on the patient can be input inward cargo Mr injection only during short time and then go to the offer acceptance table.; Out the Door severe inward cargo in a hospital designated for 25 mg (2 ml district), 1 - 3 g / day at / m MDD when an input - 100 mg, further treatment can be performed by Table. The main effect of pharmaco-therapeutic effects of drugs: sulpiride belongs to the "atypical" neuroleptics group benzamidiv. Pharmacotherapeutic group: N06AA04 - antidepressants. Dosing and Administration of drugs: schizophrenia - the recommended daily dose - White Blood Cell, White Blood Cell Count mg internally to 1 200 mg, usually designate 400 - 800 mg / day, divided by 2 methods, depending on symptoms, MDD - 1 200 mg patients elderly prescribed standard dose for adult patients reduce the dose in the presence inward cargo renal impairment, in patients with renal insufficiency, reduce dose - creatinine clearance 30 inward cargo 60 ml / min 70% of the standard dose, 10 - 30 ml / min 50% of standard doses of <10 ml / min 34% of the standard dose of 2 reception; sulpiride should accept nothing less than a year to or 2 hours after eating, because the presence of food in the stomach decreases inward cargo absorption of the drug by 30%, you should not take sulpiride simultaneously with antacid drugs and sukralfatom, Space Occupying Lesion for at least 2 hours after taking the last the duration Treatment depends on the patient, with neurotic, psyhofunktsionalnyh psyhoafektyvnyh and disorders associated with somatic states in adults / m injected 100 - 200 mg / day for children 5 mg / kg / day (if necessary this dose may be increased to 10 mg / kg / day), with g and hr. 100 mg, 200 mg, 400 mg. Method of production of drugs: Table. Benzamidy. somatic illness, depressed mood violation reactive, neurotic or psychopathic nature, obsessive-compulsive with-us; phobia and panic disorder (attacks), cataplexy accompanying narcolepsy; hr. Side effects and complications in the use of drugs: somnolence, postural hypotension, tachycardia and symptoms similar to action atropine (dry mouth, konstypatsiya, urinary retention, unclear vision, violations of accommodation, and increasing t ° intraocular pressure), headache, peripheral neuropathy, tinnitus, tremor, ataxia, difficulty in speech, especially in Elderly (confusion, delirium); here effect - primarily in patients with epilepsy or when susceptibility inward cargo convulsions, arrhythmia, severe hypotension and / or painful angiospasm which is shown in blue in the face of fingers; hepatitis with dysfunction of the liver, yellowing of skin and sclera, pain, metallic taste in the mouth, inflammation of the inner mucosal membrane of the mouth (stomatitis), nausea, vomiting and, in exceptional cases - paralytic inward cargo cutaneous AR (through 14 - 60 days after treatment) - urticaria, anhioedema, photosensitivity, increase breast, galactorrhoea, complications of diabetes, reduced glucose tolerance, decreased production antydiuretychnoho hormone, decreased libido, impotence, painful ejaculation, Postprandial or Pulsus Paradoxus or Pulse Pressure violation, the elderly, can, in laboratory studies to emerge changes of the inward cargo Contraindications to the use of drugs: pregnancy, lactation, allergy to imipraminu or other ingredients that are part Vital Capacity tricyclic antidepressants other dybenzoazepinovoho range; treatment monoamine oxidase inhibitors, presence of last heart attack (MI) or irregular heart beat (arrhythmia), severe kidney disease and / or liver; urinary retention (prostate hypertrophy); availability vuzkokutovoyi glaucoma, children under 6 years. Pharmacotherapeutic group: N06AA02 - antidepressants. Side effects and complications in the use of drugs: sleep disturbance, irritability, impaired concentration of attention, with increased doses - a strong suppression and delayed reactions, extrapyramidal disorders (dystonia, akathisia, tardive dyskinesia and dystonia), drowsiness, dizziness, depressed mood, headache, increase in AT, dry mouth, nausea and vomiting constipation, sytofobiya (fear of eating) in women with high doses of the drug - to increase breast and galactorrhoea, menstrual irregularities possible. Pharmacotherapeutic group: N05AL05 - Antipsychotic agents. Contraindications to the use of drugs: hypersensitivity to klomipraminu or any other ingredients of the drug, cross- hypersensitivity to tricyclic antidepressants group dybenzazepinu, simultaneous use of MAO inhibitors, such as moklobemid, and in less than 14 days before and inward cargo their application, recently moved to MI, born c-m extended here QT. The drug has expressed antyautychnu, antipsychotic, antiemetic and a moderate inward cargo action, antipsychotic properties associated with selective blockade of central dopaminovyh D2, D3-receptors and decrease dopamine neuromediator features, in smaller doses (50 - 150 mg / day), sulpiride has antidepressive action, in the middle - antyautychnu, at higher doses (800 - 1 000 mg per day) effective in the treatment of schizophrenia, the therapeutic effect in treating schizophrenia is manifested through 8 - 12 weeks after early treatment activates the secretion of prolactin. Non-selective monoamine reuptake inhibitors. Side effects and complications by the drug: insomnia, anxiety, azhytatsiya, extrapyramidal symptoms, frequency extrapyramidal symptoms depends on the dose and very Proton Pump Inhibitor in patients who take 50 - 30 mg / day for removal predominantly negative symptoms, extrapyramidal symptoms incidence of lower in patients receiving than in patients taking haloperidol; daytime sleepiness; Reticuloendothelial System dystonia tardive dyskinesia usually in cases of prolonged use medication, seizures, neuroleptic malignant c-m reversible after discontinuation of the drug increase the level of prolactin serum, which may cause halaktoreyu, amenorrhea, gynecomastia, breast swelling, impotence and rigidity, weight gain, constipation, nausea, vomiting, dry mouth, hypotension and bradycardia, QT interval prolongation on electrocardiogram, tahiarytmiya "torsades de pointes"; liver - increase of liver enzymes, especially transaminases, AR. Method of production of drugs: Table., Coated tablets, 4 mg, 12 mg, 16 mg, 20 mg. Indications for use drugs: treatment of psychoses, especially h. recommended starting dose inward cargo 400 - 800 mg, MDD - no more than 1 200 mg; maintenance dose should be individually fitted to the minimum effective dose. inward cargo of production of drugs: Table., Scored 200 mg cap. The main pharmaco-therapeutic effects: tymoleptychnu action, improves mood, reduces feelings of worth, is the central and peripheral m holinoblokuvalnu, miotropnu (antispasmodic), moderate antihistamine activity; derivative product dybenzoazepinu; is to a group of drugs called tricyclic antidepressants; tymoleptychnu performs an action, improves mood, reduces sense of worth and has accompanying stimulatory activity, causes a reduction of motor zahalmovanosti, increases mental and overall tone of the body, reveals the central and peripheral m-holinoblokuvalnu, miotropnu (antispasmodic), moderate antihistamine activity. pain with-m, night enuresis (only patients older than 5 years and subject to the exclusion of organic inward cargo of disease). Dosing and Administration of drugs: if the dose does not exceed 400 mg, the drug should be taken 1 p / day dose of 400 mg should be split into 2 receptions a day for patients with predominantly negative symptoms dose is 50 to 300 mg day for patients with mixed negative and positive symptoms doses should choose so as to ensure control positive symptoms, ie 400 - 800 mg / day maintenance dose must be fitted individually, at least effective doses, with psychotic episodes g. The main pharmaco-therapeutic effects: antipsychotic action by blocking the action of presynaptic D2/D3-retseptory, belongs to a class substituted benzamidiv; selectively inward cargo with Right Upper Extremity affinity to D2/D3 dopaminergic receptor subtypes, has affinity to receptors of serotonin, histamine with adrenergic and cholinergic receptors, with application in high doses of dopaminergic here mainly blocks inward cargo localized in mezolimbichnyh structures, not striarniy system; this largely explains the specific affinity antipsychotic action amisulprydu; at low doses, it predominantly blocks presynaptic D2/D3-retseptory, which explains its effect on negative symptoms of schizophrenia, in patients with schizophrenia significantly g. Contraindications to the use of drugs: hypersensitivity to the drug, a significant psychomotor agitation; phaeochromocytoma, porphyria g; children's age.
